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Design, Synthesis, Biological Activity and Molecular Docking Study of Coumarin Derivatives Bearing 2-Methylbiphenyl Moiety
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2019, 卷号: 35, 期号: 3, 页码: 410-417
作者:
Ma Junjie
;
Huang Kun
;
Ni Xin
;
Chen Roufen
;
Xu Boxuan
;
Wang Cuifang
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/02/02
GROWTH
POTENT
Coumarin
2-Methylbiphenyl
Anticancer activity
PD-1/PD-L1 inhibitory activity
Molecular docking
Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372
作者:
Zhang Lan
;
Deng Xinshan
;
Wu Jiaofeng
;
Meng Guangpeng
;
Liu Congchong
;
Chen Guzhou
;
Zhao Qingchun
;
Hu Chun
收藏
  |  
浏览/下载:151/0
  |  
提交时间:2021/02/02
MOLECULAR TARGETED DRUGS
TYROSINE KINASE
CANCER-CELLS
EGFR
RESISTANCE
POTENT
DISCOVERY
NSCLC
Anticancer activity
Epidemal growth factor receptor(EGFR) inhibitor
N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative
Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372
作者:
Zhang Lan
;
Deng Xinshan
;
Wu Jiaofeng
;
Meng Guangpeng
;
Liu Congchong
;
Chen Guzhou
;
Zhao Qingchun
;
Hu Chun
收藏
  |  
浏览/下载:146/0
  |  
提交时间:2021/02/02
MOLECULAR TARGETED DRUGS
TYROSINE KINASE
CANCER-CELLS
EGFR
RESISTANCE
POTENT
DISCOVERY
NSCLC
Anticancer activity
Epidemal growth factor receptor(EGFR) inhibitor
N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative
Design, Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives Bearing Semicarbazone Moiety as Antitumor Agents
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 6, 页码: 958-963
作者:
Ma Junjie
;
Hu Gang
;
Xie Lijun
;
Chen Lei
;
Xu Boxuan
;
Gong Ping
收藏
  |  
浏览/下载:126/0
  |  
提交时间:2021/02/02
POTENT
INHIBITORS
ONCRASIN-1
DISCOVERY
Benzothiazole
Semicarbazone
Antitumor activity
Design, Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives Bearing Semicarbazone Moiety as Antitumor Agents
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 6, 页码: 958-963
作者:
Ma Junjie
;
Hu Gang
;
Xie Lijun
;
Chen Lei
;
Xu Boxuan
;
Gong Ping
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2021/02/02
POTENT
INHIBITORS
ONCRASIN-1
DISCOVERY
Benzothiazole
Semicarbazone
Antitumor activity
Design, Synthesis and Antitumor Activity of Novel 6,7-Dimethoxyquinazoline Derivatives Containing Diaryl Urea Moiety
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 5, 页码: 766-773
作者:
Hou Yunlei
;
Wu Shasha
;
Ma Longsheng
;
Bai Jinying
;
Liu Zijian
;
Zhao Yanfang
收藏
  |  
浏览/下载:123/0
  |  
提交时间:2021/02/02
RECEPTOR TYROSINE KINASES
BIOLOGICAL EVALUATION
HIGHLY POTENT
INHIBITOR
IDENTIFICATION
GROWTH
DISCOVERY
SORAFENIB
EGFR
6,7-Dimethoxyquinazoline derivative
Diaryl urea scaffold
Cytotoxic activity
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives
期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
作者:
Sun ChiYu
;
Li YangSheng
;
Shi AiLong
;
Li YaFei
;
Cao RuiFang
;
Ding HuaiWei
;
Yin QingQing
;
Zhang LiJuan
;
Zheng HuaChuan
;
Song HongRui
收藏
  |  
浏览/下载:153/0
  |  
提交时间:2021/02/02
HEDGEHOG SIGNALING PATHWAY
BASAL-CELL CARCINOMA
INHIBITORS
DISCOVERY
DESIGN
ANTAGONISTS
IDENTIFICATION
VISMODEGIB
CANCER
POTENT
Aryl cycloaliphatic amine
Antiproliferative activity
Hedgehog signaling
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives
期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
作者:
Sun ChiYu
;
Li YangSheng
;
Shi AiLong
;
Li YaFei
;
Cao RuiFang
;
Ding HuaiWei
;
Yin QingQing
;
Zhang LiJuan
;
Zheng HuaChuan
;
Song HongRui
收藏
  |  
浏览/下载:142/0
  |  
提交时间:2021/02/02
HEDGEHOG SIGNALING PATHWAY
BASAL-CELL CARCINOMA
INHIBITORS
DISCOVERY
DESIGN
ANTAGONISTS
IDENTIFICATION
VISMODEGIB
CANCER
POTENT
Aryl cycloaliphatic amine
Antiproliferative activity
Hedgehog signaling
Synthesis and Antitumor Activities of Novel 4-Morpholinothieno3,2-dpyrimidine Derivatives
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2014, 卷号: 30, 期号: 1, 页码: 75-81
作者:
Song Kaizhen
;
Ma Junjie
;
Wang Xiao
;
Gong Ping
;
Zhao Yanfang
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/02/02
CANCER
POTENT
INHIBITOR
KINASE
2-Hydrazinyl-4-morpholinothieno3,2-dpyrimidine
Antitumor activity
Cytotoxic activity
Pharmacophore-based design, synthesis, and biological evaluation of novel 3-((3,4-dichlorophenyl)(4-substituted benzyl)amino) propanamides as cholesteryl ester transfer protein (CETP) inhibitors
期刊论文
CHINESE CHEMICAL LETTERS, 2014, 卷号: 25, 期号: 2, 页码: 299-304
作者:
Zhao DongMei
;
Li WenYan
;
Shi YuFang
;
Xiong XuQiong
;
Song Shuai
;
Hao ChenZhou
;
Cheng MaoSheng
;
Shen JingKang
收藏
  |  
浏览/下载:163/0
  |  
提交时间:2021/02/02
CHIRAL N,N-DISUBSTITUTED TRIFLUORO-3-AMINO-2-PROPANOLS
POTENT INHIBITORS
DISCOVERY
TRANSPORT
Cholesteryl ester transfer protein
CETP inhibitors
Pharmacophore
Virtual screening
Synthesis