Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography-Triple Quadrupole Mass Spectrometry with Isotope Internal Standards

IMR OpenIR

	Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography-Triple Quadrupole Mass Spectrometry with Isotope Internal Standards
其他题名	Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography- Triple Quadrupole Mass Spectrometry with Isotope Internal Standards
	Wang RuiGuo 1; Zhang Su 1; Dong ShuJun 1; Wei ShuLin 1; Zhang TianShu 2; Yang HaoSen 1; Cheng Jie 1; Wang PeiLong 1; Su XiaoOu 1
	2018
发表期刊	CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
ISSN	0253-3820
卷号	46 期号:12 页码:2019-2024
摘要	A method was developed for determination of 6 kinds of indictor polychlorinated biphenyls in animal feed by chromatography-tandem mass spectrometry (GC-MS/MS). Analytical procedure consisted of accelerate solvent extraction (ASE), lipid removal with 44% acidic silica and clean-up using a column packed with multilayer silica. The analytes were separated on a DB-5MS capillary column, detected with electron ionization (EI) and multiple reaction monitor mode (MRM), and quantified using isotope dilution technique. The result showed that the calibration curves with good correlation coefficients (R-2 >0. 999) were obtained in the concentration range of 0.1-500.0 ng/mL. The average relative response factors of PCBs in calibration solvent were 1.08-1.21, and the limit of quantification were 5.5-9.2 pg/g. The average recoveries of PCBs in animal feed at two spiked concentration levels ranged from 92.8% to 109.7% with relative standard deviations (RSDs) of 1.6%-14.8% (n = 5), and the average recoveries of quantitative internal standards were 32.6%-90.2%. Then the proposed method was successfully applied to detect the compound feed samples from the surrounding area of Beijing, and it was found that the 6 kinds of indictor PCBs were detected in all samples (n = 10) with the total concentration ranges of 54.7-191.7 pg/g, which were far below the limit standard (10 mu g/kg) of Chinese National Standards.
关键词	PCBS EXTRACTION DIOXINS PCDD/FS WATER FOOD Indicator polychlorinated biphenyls Feed Gas-chromatography-tandem mass spectrometry
收录类别	CSCD
语种	英语
资助项目	[National Key R&D Program of China] ; [Shanghai Agriculture Applied Technology Development Program, China] ; [Chinese Academy of Agricultural Science Basal Research Fund]
CSCD记录号	CSCD:6385184
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/86716
专题	中国科学院金属研究所
作者单位	1.中国科学院亚热带农业生态研究所 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Wang RuiGuo,Zhang Su,Dong ShuJun,et al. Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography-Triple Quadrupole Mass Spectrometry with Isotope Internal Standards[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2018,46(12):2019-2024.
APA	Wang RuiGuo.,Zhang Su.,Dong ShuJun.,Wei ShuLin.,Zhang TianShu.,...&Su XiaoOu.(2018).Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography-Triple Quadrupole Mass Spectrometry with Isotope Internal Standards.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,46(12),2019-2024.
MLA	Wang RuiGuo,et al."Determination of Ultratrace Indicator Polychlorinated Biphenyls in Animal Feed by Gas Chromatography-Triple Quadrupole Mass Spectrometry with Isotope Internal Standards".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 46.12(2018):2019-2024.