Effect of Gallium Addition on Mechanical and Antibacterial Properties of 304L Stainless Steel

doi:10.11900/0412.1961.2022.00351

IMR OpenIR

	Effect of Gallium Addition on Mechanical and Antibacterial Properties of 304L Stainless Steel
	Meng Yujia 1,2; Xi Tong 2; Yang Chunguang 2; Zhao Jinlong 2; Zhang Xinrui 2; Yu Yingjie 2; Yang Ke 2
通讯作者	Yang Chunguang(cgyang@imr.ac.cn)
	2024-07-11
发表期刊	ACTA METALLURGICA SINICA
ISSN	0412-1961
卷号	60 期号:7 页码:890-900
摘要	As a new antibacterial metal element, Ga is widely used in the medical field and always added to compounds in ionic form to form Ga complexes for medicinal use. However, related research on the mechanical properties, antibacterial properties, and antibacterial mechanism of Ga-bearing alloys is still very limited. In this work, the effect of Ga addition on the mechanical properties of 304L austenitic stainless steel (304L SS) after solution treatment was investigated via metallographic observations and tensile strength and hardness tests. Moreover, the antibacterial properties of Ga-bearing 304L stainless steel (304L-Ga SS) were tested using plate counting and the activity state of bacteria on the surface of the material was detected using SEM. Based on the known Ga ion sterilization principle, the antibacterial mechanism of 304L-Ga SS was preliminarily discussed using the reactive oxygen species (ROS) fluorescence reaction and ion dissolution results of the material in different solution tests. Results showed that the structure of 304L-Ga SS is still austenitic like that of 304L SS. The Ga addition increases the yield strength and elongation of the material but decreases its tensile strength and hardness. The change in strength and elongation is the result of the synergistic effect of the increase in stacking fault energy and the solid solution strengthening. The Ga addition also slightly increases the lattice constant of stainless steel due to the replacement solid solution effect. In the passive film of 304L-Ga SS, Ga exists in alloy form. Because of their similarity to Fe ions, Ga ions dissolved from Ga in the passive film are inhaled into bacteria cells and cause high expression of ROS in the bacteria, causing oxidative stress, and bactericidal effect. Contact sterilization is one of the main bactericidal mechanisms of 304L-Ga SS. Adequate contact between the bacteria and stainless steel improves the dissolution of Ga due to the proton (H+) depletion reaction in the bacteria. At the same time, the production of additional ROS during the proton consumption reaction further enhances the antibacterial effect.
关键词	Ga-bearing stainless steel microstructure mechanical property contact antibacterial
DOI	10.11900/0412.1961.2022.00351
收录类别	SCI
语种	英语
WOS研究方向	Metallurgy & Metallurgical Engineering
WOS类目	Metallurgy & Metallurgical Engineering
WOS记录号	WOS:001260210800004
出版者	SCIENCE PRESS
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/187969
专题	中国科学院金属研究所
通讯作者	Yang Chunguang
作者单位	1.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shi Changxu Adv Mat Innovat Ctr, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Meng Yujia,Xi Tong,Yang Chunguang,et al. Effect of Gallium Addition on Mechanical and Antibacterial Properties of 304L Stainless Steel[J]. ACTA METALLURGICA SINICA,2024,60(7):890-900.
APA	Meng Yujia.,Xi Tong.,Yang Chunguang.,Zhao Jinlong.,Zhang Xinrui.,...&Yang Ke.(2024).Effect of Gallium Addition on Mechanical and Antibacterial Properties of 304L Stainless Steel.ACTA METALLURGICA SINICA,60(7),890-900.
MLA	Meng Yujia,et al."Effect of Gallium Addition on Mechanical and Antibacterial Properties of 304L Stainless Steel".ACTA METALLURGICA SINICA 60.7(2024):890-900.