The effects of process parameters on the mechanical properties and degradation behavior of Fe/HA biodegradable materials

doi:10.1177/08853282241310592

IMR OpenIR

	The effects of process parameters on the mechanical properties and degradation behavior of Fe/HA biodegradable materials
	Feng, Yuzhen 1; Huang, Nan 1; Guo, Jing 1; Chen, Shuwen 1; Teng, Yingxue 1; Chen, Shanshan 2
通讯作者	Teng, Yingxue(tengyingxue_2007@163.com) ; Chen, Shanshan()
	2024-12-20
发表期刊	JOURNAL OF BIOMATERIALS APPLICATIONS
ISSN	0885-3282
页码	14
摘要	HA/Fe composites were prepared by powder metallurgy. The effects of ball milling time, pressing pressure, and sintering temperature on the porosity and hardness of the composites were investigated, and their mechanical properties and biocompatibility were evaluated. The results show that as the ball milling time increases (30 similar to 60min), the average particle size initially decreases and then increases (82.91 similar to 53.49 similar to 77.98 mu m). Additionally, an appropriate increase in pressing pressure and sintering temperature can decrease the composite's porosity and increase its hardness. When the pressing pressure is 27 KN and the sintering temperature is 1000 degrees C, the composite material has excellent mechanical properties (hardness 268.5 Hv, compressive strength 106.736 MPa) and good in vitro biocompatibility. The hemolysis rate of the sample was 1.719518 %. When the concentration of the extract was 50 %, the cell proliferation rate could reach 136.26 %. Furthermore, the degradation properties of the composites were studied. At 12 months the corrosion rate of HA/Fe composites reached 0.3173 mm/a. It was also observed varying degradation mechanisms was different in different soaking cycles, and the dominant degradation mechanism was gradually changed from HA in the early stage to Fe in the later stage, which played a positive guiding role in the development of iron matrix composites with different degradation rates.
关键词	Bio-composite HA fe degradation biocompatibility
资助者	National Natural Science Foundation of China
DOI	10.1177/08853282241310592
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[52074149]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:001380543700001
出版者	SAGE PUBLICATIONS LTD
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/181122
专题	中国科学院金属研究所
通讯作者	Teng, Yingxue; Chen, Shanshan
作者单位	1.Univ Sci & Technol Liaoning, Sch Mat & Met, 185 Qianshan Middle Rd,High tech Zone, Anshan 114051, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shi Changxu Innovat Ctr Adv Mat, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Feng, Yuzhen,Huang, Nan,Guo, Jing,et al. The effects of process parameters on the mechanical properties and degradation behavior of Fe/HA biodegradable materials[J]. JOURNAL OF BIOMATERIALS APPLICATIONS,2024:14.
APA	Feng, Yuzhen,Huang, Nan,Guo, Jing,Chen, Shuwen,Teng, Yingxue,&Chen, Shanshan.(2024).The effects of process parameters on the mechanical properties and degradation behavior of Fe/HA biodegradable materials.JOURNAL OF BIOMATERIALS APPLICATIONS,14.
MLA	Feng, Yuzhen,et al."The effects of process parameters on the mechanical properties and degradation behavior of Fe/HA biodegradable materials".JOURNAL OF BIOMATERIALS APPLICATIONS (2024):14.