Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial

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	Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial
	Liu Shiwei 1; Guo Jie 1; Wu Weikang 2; Chen Zeliang 3; Zhang Ning 1
	2019
发表期刊	CHINESE JOURNAL OF INTEGRATIVE MEDICINE
ISSN	1672-0415
卷号	25 期号:1 页码:16-22
摘要	ObjectiveTo evaluate Chinese medicine (CM) formula Bazheng Powder (???) as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).MethodsA randomized double-blinded trial was performed. Eligible female patients with RUTI were recruited from one hospital and two community health centers. By using a blocked randomization scheme, participants were randomized to receive a CM formula (10 herbs) for 4 weeks or antibiotics for 1 week, followed by 3 weeks of placebo. Clinical cure rate and microbiological cure and recurrence after treatment were evaluated.ResultsA total 122 eligible patients were enrolled, with 61 cases in each group. The clinical cure rate by the intentto- treatment approach was 90.2% for the CM group and 82.0% for the antibiotics group (P>0.05). Bacteria were cleared from 88.5% (54/61) of patients in the CM group and 82.0% (50/61) in the antibiotics group. The recurrence rate in recovered patients at the 6-month follow-up was 9.1% (5/61) and 14.0 (7/61) in the CM and antibiotics groups, respectively (P>0.05).ConclusionCM formula Bazheng Powder is a good alternative option for RUTI treatment. (Registration No. NCT01745328)
关键词	DIAGNOSIS Chinese medicine recurrent urinary tract infection randomized control trial
收录类别	CSCD
语种	英语
资助项目	[Chinese Academy of Traditional Chinese Medicine Joint Innovation Research Project] ; [Traditional Chinese Medicine Dominant Disease Clinical Research Project] ; [Capital Featured Clinical Application and Promotion Project, China]
CSCD记录号	CSCD:6410946
引用统计	被引频次：1[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/153684
专题	中国科学院金属研究所
作者单位	1.Chinese Acad Chinese Med Sci, Wangjing Hosp, Department Nephrol & Endocrinol, Beijing 100102, Peoples R China Wangjing Hosp Department Nephrol & Endocrinol 2.中国科学院广州地球化学研究所 3.Acad Mil Med Sci, Institute Dis Control & Prevent, Beijing 100071, Peoples R China 4.中国科学院金属研究所
推荐引用方式 GB/T 7714	Liu Shiwei,Guo Jie,Wu Weikang,et al. Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2019,25(1):16-22.
APA	Liu Shiwei,Guo Jie,Wu Weikang,Chen Zeliang,&Zhang Ning.(2019).Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,25(1),16-22.
MLA	Liu Shiwei,et al."Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 25.1(2019):16-22.