Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease

IMR OpenIR

	Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease
其他题名	Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease
	Liang Ming 1; Han Yaling 2; Wang Geng 2; Yao Tianming 2; Sun Jingyang 2; Li Fei 2; Xu Kai 2; Wang Bin 2; Li Yi 2; Rong Jingjing 2; Wang Xiaozeng 2
	2014
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	127 期号:6 页码:1052-1056
摘要	Background The lack of medical facilities causes delayed diagnosis and treatment of coronary heart disease in remote mountainous area and/or at disaster site. The miniature mobile cardiac catheterization laboratory was developed to be an intervention platform for coronary heart disease diagnosis and treatment by our team. Pre-clinical research indicated that the miniature mobile cardiac catheterization laboratory performed well in the rescue of critical cardiovascular diseases, even ST-segment elevation myocardial infarction. The present study aimed to evaluate the clinical safety and timeliness of the miniature mobile cardiac catheterization laboratory for emergent coronary interventional diagnosis and treatment.
其他摘要	Background The lack of medical facilities causes delayed diagnosis and treatment of coronary heart disease in remote mountainous area and/or at disaster site. The miniature mobile cardiac catheterization laboratory was developed to be an intervention platform for coronary heart disease diagnosis and treatment by our team. Pre-clinical research indicated that the miniature mobile cardiac catheterization laboratory performed well in the rescue of critical cardiovascular diseases, even ST-segment elevation myocardial infarction. The present study aimed to evaluate the clinical safety and timeliness of the miniature mobile cardiac catheterization laboratory for emergent coronary interventional diagnosis and treatment. Methods X-ray radiation safety and disinfection efficacy in the miniature mobile cardiac catheterization laboratory were tested during working status. Coronary angiography and/or percutaneous coronary intervention were performed in remote mountainous areas on patients who were first diagnosed as having coronary heart disease by senior interventional cardiologists. The percutaneous coronary intervention procedures and results from patients in the miniature mobile cardiac catheterization laboratory were compared with patients who were treated in the hospital catheter lab. Results The X-ray radiation dosages in the miniature mobile cardiac catheterization laboratory were 39.55 μGy/s, 247.4 μGy/h, 90.3 μGy/h and 39.4 μGy/h which were corresponded to 0 m, 1 m, 2 m and 3 m away from the tube central of the medium C-arm. And the radiation dosages used in the miniature mobile cardiac catheterization laboratory were less than the corresponding positions in the hospital catheter lab. The numbers of bacteria colonies in the miniature mobile cardiac catheterization laboratory in different environments range from (60±8) cfu/m~3 to (120±10) cfu/m~3 and met the demands of percutaneous coronary intervention. A total of 17 patients who received angiography in the miniature mobile cardiac catheterization laboratory, eight received percutaneous coronary intervention. The operations were all successfully accomplished without intraoperative and postoperative complications. The average angiography and percutaneous coronary intervention times were 35±9 minutes and 55±11 minutes, respectively. There was no significant difference in immediate percutaneous coronary intervention results between the miniature mobile cardiac catheterization laboratory and the catheter lab. Conclusions It is safe and feasible to carry out clinical interventional diagnosis and treatment in the miniature mobile cardiac catheterization laboratory as determined by this research. The miniature mobile cardiac catheterization laboratory may be considered a newly developed diagnosis and treatment platform for rescuing coronary heart disease patients in remote mountainous areas and/or at disaster sites.
关键词	ACUTE MYOCARDIAL-INFARCTION HANSHIN-AWAJI EARTHQUAKE INTERVENTION CARDIOLOGY MORTALITY coronary heart disease diagnosis treatment percutaneous coronary intervention mobile catheter lab
收录类别	CSCD
语种	英语
资助项目	[Special Project of "the Eleventh Five-Year Plan" for Medical Science and Technology Research of People's Liberation Army] ; [Key Project of "the Twelfth Five-Year Plan" for Medical Science and Technology Research of People's Liberation Army]
CSCD记录号	CSCD:5080343
引用统计	被引频次：2[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/153384
专题	中国科学院金属研究所
作者单位	1.Dalian Med University, Affiliated Hosp 2, Dept Cardiol, Dalian 116027, Liaoning, Peoples R China 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Liang Ming,Han Yaling,Wang Geng,et al. Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease[J]. CHINESE MEDICAL JOURNAL,2014,127(6):1052-1056.
APA	Liang Ming.,Han Yaling.,Wang Geng.,Yao Tianming.,Sun Jingyang.,...&Wang Xiaozeng.(2014).Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease.CHINESE MEDICAL JOURNAL,127(6),1052-1056.
MLA	Liang Ming,et al."Clinical feasibility and safety of a novel miniature mobile cardiac catheterization laboratory in diagnosis and treatment for coronary heart disease".CHINESE MEDICAL JOURNAL 127.6(2014):1052-1056.