Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate

doi:10.11900/0412.1961.2017.00285

IMR OpenIR

	Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate
	Yu Xiaoming 1; Tan Lili 1; Liu Zongyuan 1; Yang Ke 1; Zhu Zhonglin 2; Li Yangde 3
通讯作者	Tan Lili(lltan@imr.ac.cn)
	2018-06-01
发表期刊	ACTA METALLURGICA SINICA
ISSN	0412-1961
卷号	54 期号:6 页码:943-949
摘要	Currently, metallic biomaterials used in orthopedics are normally bioinert which is hard to integrate with the bone tissue inducing aseptic loosening and easy to get infection, which is the main reason of implantation failure. Mg base metals are considered to be a new generation of revolutionary metallic biomaterials due to its similar density and mechanical properties with natural bone, good biocompatibility, degradability in the body as well as the biological functional ability to promote new bone tissue formation. In addition, the degradation of Mg may increase the local pH which can inhibit the growth of bacteria. In this work, pure Mg coating was deposited on Ti6Al4V substrate by arc ion plating. The effects of different working pressures on the surface quality and properties of Mg coating were investigated. The degradation, antibacterial and biosafety properties were studyied. The results showed that the pure Mg coating can be deposited on the surface of Ti6Al4V substrate and the coating was uniform and smooth. The immersion test in vitro showed that the degradation was very fast because of galvanic corrosion, and the whole process was finished in about one week. The results of antimicrobial experiments showed that the Mg coating can kill staphylococcus aureus and showed good antibacterial function. The results of cytotoxicity test showed that Mg coating promoted rabbit bone marrow mesenchymal stem cells (rBMSCs) growth and proliferation.
关键词	Ti alloy pure Mg coating bioproperty
资助者	National Natural Science Foundation of China ; National Key Research and Development Program of China
DOI	10.11900/0412.1961.2017.00285
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81500897] ; National Natural Science Foundation of China[81400528] ; National Key Research and Development Program of China[2016YFC1101804]
WOS研究方向	Metallurgy & Metallurgical Engineering
WOS类目	Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000433007400014
出版者	SCIENCE PRESS
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/128469
专题	中国科学院金属研究所
通讯作者	Tan Lili
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Jiangsu OKANI Med Technol Co Ltd, Suzhou 215123, Peoples R China 3.Dong Guan EONTC Co Ltd, Dongguan 523808, Peoples R China
推荐引用方式 GB/T 7714	Yu Xiaoming,Tan Lili,Liu Zongyuan,et al. Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate[J]. ACTA METALLURGICA SINICA,2018,54(6):943-949.
APA	Yu Xiaoming,Tan Lili,Liu Zongyuan,Yang Ke,Zhu Zhonglin,&Li Yangde.(2018).Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate.ACTA METALLURGICA SINICA,54(6),943-949.
MLA	Yu Xiaoming,et al."Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate".ACTA METALLURGICA SINICA 54.6(2018):943-949.